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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Deficiency of RbAp48 protein and memory loss ： ウィキペディア英語版 Deficiency of RbAp48 protein and memory loss Memory is commonly referred to as the ability to encode, store, retain and subsequently recall information and past experiences in the human brain. This process involves many proteins, one of which is the Histone-binding protein RbAp48 (also known as RBBP4 or NURF55), encoded by the RBBP4 gene in humans. ==Function== RbAp48, also known as RBBP4 gene encodes a nuclear protein, which belongs to a highly conserved family of WD40 repeat. This gene is present in many protein complexes that are involved in Histone acetylation and deacetylation processes as well as chromatin assembly. This gene also belongs to the Mi-2/NuRD complex, also known as ''nucleosome remodeling deacetylase complex'' which plays a role in both ATP-dependent chromatin remodeling and histone deacetylase activities. This protein is also part of a co-repressor complex which is an important component of transcriptional silencing. This gene is widely available and can be found in several cellular proteins which bind directly to the retinoblastoma protein to regulate growth and cell proliferation. This protein also found in the transcriptional repression of E2F-responsive genes, which are a group of genes that encode for a family of transcription factors.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Deficiency of RbAp48 protein and memory loss」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.